Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0006508 | biological_process | proteolysis |
A | 0007596 | biological_process | blood coagulation |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0005509 | molecular_function | calcium ion binding |
B | 0006508 | biological_process | proteolysis |
B | 0007596 | biological_process | blood coagulation |
D | 0004252 | molecular_function | serine-type endopeptidase activity |
D | 0005576 | cellular_component | extracellular region |
D | 0006508 | biological_process | proteolysis |
D | 0007596 | biological_process | blood coagulation |
E | 0004252 | molecular_function | serine-type endopeptidase activity |
E | 0005509 | molecular_function | calcium ion binding |
E | 0006508 | biological_process | proteolysis |
E | 0007596 | biological_process | blood coagulation |
G | 0005102 | molecular_function | signaling receptor binding |
G | 0005577 | cellular_component | fibrinogen complex |
G | 0007596 | biological_process | blood coagulation |
G | 0030168 | biological_process | platelet activation |
G | 0051258 | biological_process | protein polymerization |
H | 0005102 | molecular_function | signaling receptor binding |
H | 0005577 | cellular_component | fibrinogen complex |
H | 0030168 | biological_process | platelet activation |
H | 0051258 | biological_process | protein polymerization |
I | 0005102 | molecular_function | signaling receptor binding |
I | 0005577 | cellular_component | fibrinogen complex |
I | 0030168 | biological_process | platelet activation |
I | 0051258 | biological_process | protein polymerization |
J | 0005102 | molecular_function | signaling receptor binding |
J | 0005577 | cellular_component | fibrinogen complex |
J | 0007596 | biological_process | blood coagulation |
J | 0030168 | biological_process | platelet activation |
J | 0051258 | biological_process | protein polymerization |
K | 0005102 | molecular_function | signaling receptor binding |
K | 0005577 | cellular_component | fibrinogen complex |
K | 0030168 | biological_process | platelet activation |
K | 0051258 | biological_process | protein polymerization |
L | 0005102 | molecular_function | signaling receptor binding |
L | 0005577 | cellular_component | fibrinogen complex |
L | 0030168 | biological_process | platelet activation |
L | 0051258 | biological_process | protein polymerization |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE 0G6 B 1 |
Chain | Residue |
B | CYS42 |
B | GLU192 |
B | GLY193 |
B | SER195 |
B | SER214 |
B | TRP215 |
B | GLY216 |
B | GLY226 |
B | HIS57 |
B | CYS58 |
B | TRP60 |
B | ASN98 |
B | LEU99 |
B | ASP189 |
B | ALA190 |
B | CYS191 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE 0G6 E 1 |
Chain | Residue |
E | PO42 |
E | HIS57 |
E | CYS58 |
E | TYR60 |
E | ASN98 |
E | LEU99 |
E | ILE174 |
E | ALA190 |
E | CYS191 |
E | GLU192 |
E | GLY193 |
E | SER195 |
E | SER214 |
E | TRP215 |
E | GLY216 |
E | GLY219 |
E | CYS220 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE PO4 B 248 |
Chain | Residue |
B | LEU41 |
B | GLY193 |
D | ARG15 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PO4 E 2 |
Chain | Residue |
E | 0G61 |
E | LEU41 |
E | CYS42 |
E | CYS58 |
E | LYS60 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
B | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
Chain | Residue | Details |
B | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
I | SER42 | |
L | SER42 | |
B | SER195 | |
E | HIS57 | |
E | ASP102 | |
E | SER195 | |
Chain | Residue | Details |
G | SER31 | |
J | SER31 | |
Chain | Residue | Details |
G | SER37 | |
J | SER37 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | GLY193 | |
B | HIS57 | |
site_id | CSA2 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP102 | |
E | SER195 | |
E | GLY193 | |
E | HIS57 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | HIS57 | |
B | GLY196 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP102 | |
E | SER195 | |
E | HIS57 | |
E | GLY196 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
B | ASP102 | |
B | SER195 | |
B | HIS57 | |
site_id | CSA6 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP102 | |
E | SER195 | |
E | HIS57 | |