2A2X
Orally Active Thrombin Inhibitors in Complex with Thrombin Inh12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Thrombin light chain | polymer | 34 | 3848.3 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II |
| 3 | C (P) | synthetic peptide | polymer | 11 | 1514.6 | 1 | BIRD (PRD_000480) | Synthetic | |
| 4 | D (H) | N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({6-[AMINO(IMINO)METHYL]PYRIDIN-3-YL}METHYL)-N~2~-METHYL-L-ALANINAMIDE | non-polymer | 446.5 | 1 | Chemie (NA9) | |||
| 5 | E, F, G (L, H, P) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35143.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 446.5 | |
| All* | Total formula weight | 35589.6 |
