2A2C
x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-acetylgalactosamine kinase | polymer | 478 | 52788.6 | 1 | UniProt (Q01415) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544) | Homo sapiens | GalNAc kinase, Galactokinase 2 |
| 2 | B (A) | 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose | non-polymer | 301.2 | 1 | Chemie (NG1) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 7 | G (A) | water | water | 18.0 | 457 | Chemie (HOH) |
Sequence modifications
A: 1 - 458 (UniProt: Q01415)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| Ser -16 | - | cloning artifact |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Glu -7 | - | cloning artifact |
| Asn -6 | - | cloning artifact |
| Leu -5 | - | cloning artifact |
| Tyr -4 | - | cloning artifact |
| Phe -3 | - | cloning artifact |
| Gln -2 | - | cloning artifact |
| Gly -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52788.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 811.1 | |
| All* | Total formula weight | 53599.8 |






