2A27
Human DRP-1 kinase, W305S S308A D40 mutant, crystal form with 8 monomers in the asymmetric unit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Death-associated protein kinase 2 | polymer | 321 | 37025.4 | 8 | UniProt (Q9UIK4) Pfam (PF00069) | Homo sapiens (human) | DRP-1 kinase, DAP kinase 2, DAP- kinase related protein 1, DRP-1 |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 8 | Chemie (DTT) | |||
| 3 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 320 (UniProt: Q9UIK4)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | cloning artifact |
| Ser 305 | Trp 315 | engineered mutation |
| Ala 308 | Ser 318 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 296202.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1234.0 | |
| All* | Total formula weight | 297436.8 |
