29ON
Crystal structure of the staphylococcal efflux pump QacA in the inward open state in complex with nanobody 89
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Antiseptic resistance protein | polymer | 520 | 55784.3 | 2 | UniProt (P0A0J9) | Staphylococcus aureus | Quaternary ammonium compound efflux MFS transporter |
| 2 | C, D (C, D) | Nanobody 89 | polymer | 148 | 15965.6 | 2 | Lama glama | ||
| 3 | E (A) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 1 | Chemie (PTY) | |||
| 4 | F, K (A, B) | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 751.0 | 2 | Chemie (PGT) | |||
| 5 | G, H, I, J (A) | DODECYL-ALPHA-D-MALTOSIDE | non-polymer | 510.6 | 4 | Chemie (LMU) PubChem (445456) | |||
| 6 | L (B) | OXAMIC ACID | non-polymer | 89.0 | 1 | Chemie (OXM) PubChem (974) |
Sequence modifications
A, B: 1 - 514 (UniProt: P0A0J9)
| PDB | External Database | Details |
|---|---|---|
| Leu 515 | - | expression tag |
| Glu 516 | - | expression tag |
| Val 517 | - | expression tag |
| Leu 518 | - | expression tag |
| Phe 519 | - | expression tag |
| Gln 520 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 143499.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4367.6 | |
| All* | Total formula weight | 147867.5 |
