29LK
High-resolution structure of human SHMT2 in complex with PLP-Ser (external aldimine)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine hydroxymethyltransferase, mitochondrial | polymer | 476 | 52716.9 | 4 | UniProt (P34897) | Homo sapiens (human) | SHMT,Glycine hydroxymethyltransferase,Serine methylase |
| 2 | AA, E, F, G, H... (D, A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 16 | Chemie (EDO) | |||
| 3 | I (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) PubChem (3777159) | |||
| 4 | CA, J, P, X (D, A, B, C) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) PubChem (923) | |||
| 5 | DA, K, Q, Y (D, A, B, C) | [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | non-polymer | 336.2 | 4 | Chemie (PLS) PubChem (444550) | |||
| 6 | BA (D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 7 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 995 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 210867.4 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2658.3 | |
| All* | Total formula weight | 213525.7 |
