28MB
Structure of Human Aldehyde oxidase under TCEP-reducing conditions
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aldehyde oxidase | polymer | 1338 | 147904.1 | 2 | UniProt (Q06278) | Homo sapiens (human) | Aldehyde oxidase 1,Azaheterocycle hydroxylase |
| 2 | C, D, K, L (A, B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 4 | Chemie (FES) | |||
| 3 | E, M (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 4 | F, G, H, O (A, B) | MALONATE ION | non-polymer | 102.0 | 4 | Chemie (MLI) | |||
| 5 | I, P (A, B) | PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER | non-polymer | 395.4 | 2 | Chemie (MTE) | |||
| 6 | J, Q (A, B) | DIOXOTHIOMOLYBDENUM(VI) ION | non-polymer | 161.0 | 2 | Chemie (MOS) | |||
| 7 | N (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | R, S (A, B) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 1338 (UniProt: Q06278)
| PDB | External Database | Details |
|---|---|---|
| Ala 161 | Cys 161 | engineered mutation |
| Ala 165 | Cys 165 | engineered mutation |
| Ala 170 | Cys 170 | engineered mutation |
| Ala 171 | Cys 171 | engineered mutation |
| Ala 179 | Cys 179 | engineered mutation |
| Ala 180 | Cys 180 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 295808.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3887.4 | |
| All* | Total formula weight | 299695.6 |
