28MB
Structure of Human Aldehyde oxidase under TCEP-reducing conditions
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 174 |
| Details | Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 370 |
| Details | Domain: {"description":"FAD-binding PCMH-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00718","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; for azaheterocycle hydroxylase activity","evidences":[{"source":"UniProtKB","id":"O54754","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26322824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4UHW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 46 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26322824","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26842593","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4UHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5EPG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26322824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4UHW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UHX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26322824","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26842593","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5EPG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26322824","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4UHX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
