27UH
Crystal structure of a de novo-designed VHH targeting S100A4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | S100A4_VHH-N20 | polymer | 131 | 13877.5 | 4 | synthetic construct | ||
| 2 | B, D, F, H (B, D, F, H) | Protein S100-A4 | polymer | 102 | 11832.6 | 4 | UniProt (P26447) Pfam (PF01023) | Homo sapiens (human) | Calvasculin,Metastasin,Placental calcium-binding protein,Protein Mts1,S100 calcium-binding protein A4 |
| 3 | I, J, L, M, O... (B, D, F, H) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) PubChem (271) | |||
| 4 | K (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 5 | N, Q (E, G) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 6 | AA, T, U, V, W... (H, A, B, C, D...) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
B, D, F, H: 0 - 100 (UniProt: P26447)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 102840.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 610.9 | |
| All* | Total formula weight | 103451.3 |
