26SJ
Crystal structure of MAIT A-F7 TCR-MR1-xanthine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, F (B, F) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | D, G (D, G) | Human A-F7 TCR TRAV1-2_ALPHA | polymer | 204 | 22781.3 | 2 | Homo sapiens | ||
| 4 | E, H (E, H) | Human A-F7 TCR TRBV6-1_BETA | polymer | 246 | 27677.8 | 2 | Homo sapiens | ||
| 5 | I, L (A, C) | XANTHINE | non-polymer | 152.1 | 2 | Chemie (XAN) | |||
| 6 | J, M, N, P, Q... (A, C, D, E, F...) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) PubChem (753) | |||
| 7 | K, O (A, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 8 | U (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 9 | AA, BA, CA, V, W... (F, G, H, A, B...) | water | water | 18.0 | 475 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
B, F: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 188100.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1152.0 | |
| All* | Total formula weight | 189252.1 |
