25CG
Structure of hTRPC3 E603A/V637A/K607A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, A, C, D) | Short transient receptor potential channel 3 | polymer | 836 | 95974.0 | 4 | UniProt (Q13507) | Homo sapiens (human) | TrpC3,Transient receptor protein 3,TRP-3,hTrp-3,hTrp3 |
| 2 | E, F, G, I, J... (B, A, C, D) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) PubChem (271) | |||
| 3 | H, L, P, T (B, A, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) | |||
| 4 | U, V, W, X (B, A, C, D) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
B, A, C, D: 1 - 836 (UniProt: Q13507)
| PDB | External Database | Details |
|---|---|---|
| Ala 603 | Glu 688 | engineered mutation |
| Ala 607 | Lys 692 | engineered mutation |
| Ala 637 | Val 722 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 383896.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 742.6 | |
| All* | Total formula weight | 384638.7 |
