24VE

Structure of cytosol-open ABCD4-LMBD1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lysosomal cobalamin transporter ABCD4	polymer	606	68694.1	2	UniProt (O14678)	Homo sapiens (human)	ATP-binding cassette sub-family D member 4,PMP70-related protein,P70R,Peroxisomal membrane protein 1-like,PXMP1-L,Peroxisomal membrane protein 69,PMP69
2	C (C)	Lysosomal cobalamin transport escort protein LMBD1	polymer	540	61431.4	1	UniProt (Q9NUN5)	Homo sapiens (human)	LMBD1,HDAg-L-interacting protein NESI,LMBR1 domain-containing protein 1,Nuclear export signal-interacting protein
3	D, E (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)

Sequence modifications

A, B: 1 - 606 (UniProt: O14678)

PDB	External Database	Details
Thr 304	Ala 304	variant
Lys 368	Glu 368	variant

C: 1 - 540 (UniProt: Q9NUN5)

PDB	External Database	Details
Val 395	Ile 395	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	198819.7
Non-Polymers*	Number of molecules	2
	Total formula weight	854.4
All*	Total formula weight	199674.1

*Water molecules are not included.