24BQ
Crystal structure of nuclease MYG1(H50A) bound to Mn2+ and dAC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MYG1 exonuclease | polymer | 327 | 36864.5 | 1 | UniProt (Q9HB07) Pfam (PF03690) | Homo sapiens (human) | |
| 2 | B (C) | DNA (5'-D(P*CP*A)-3') | polymer | 2 | 557.4 | 1 | synthetic construct | ||
| 3 | C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) PubChem (27854) | |||
| 4 | D, E (A, C) | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A: 43 - 369 (UniProt: Q9HB07)
| PDB | External Database | Details |
|---|---|---|
| Ala 50 | His 50 | engineered mutation |
| Ile 287 | Val 287 | conflict |
| His 353 | Arg 353 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37421.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 54.9 | |
| All* | Total formula weight | 37476.8 |
