23XO

Cryo-EM structure of human sodium/proton antiporter NHE1 in complex with Rimeporide in an outward-open conformation

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Sodium/hydrogen exchanger 1	polymer	815	90866.8	2	UniProt (P19634)	Homo sapiens (human)	APNH,Na(+)/H(+) antiporter,amiloride-sensitive,Na(+)/H(+) exchanger 1,NHE-1,Solute carrier family 9 member 1
2	C, D (A, B)	~{N}-carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide	non-polymer		333.4	2	Chemie (A1E6E)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	181733.5
Non-Polymers*	Number of molecules	2
	Total formula weight	666.8
All*	Total formula weight	182400.3

*Water molecules are not included.