23EW
Cryo-EM structure of human ATR-ATRIP complex with Berzosertib
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase ATR | polymer | 2644 | 301756.8 | 2 | UniProt (Q13535) | Homo sapiens (human) | Ataxia telangiectasia and Rad3-related protein,FRAP-related protein 1 |
| 2 | C, D (C, D) | ATR-interacting protein | polymer | 791 | 85940.7 | 2 | UniProt (Q8WXE1) | Homo sapiens (human) | ATM and Rad3-related-interacting protein |
| 3 | E, F (A, B) | VE-822 | non-polymer | 463.6 | 2 | Chemie (A1EIE) PubChem (59472121) | |||
| 4 | G, H (C, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 775394.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1057.9 | |
| All* | Total formula weight | 776452.8 |
