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23ES

Crystal structure of human PKMYT1 protein kinase domain with Naphthyridinone Inhibitor compound 11

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinasepolymer28631572.92UniProt (Q99640)
Pfam (PF00069)
Homo sapiens (human)Myt1 kinase
2C, F
(A, B)
3-azanyl-5-chloranyl-4-(7-fluoranyl-2H-indazol-4-yl)-7-methyl-1H-1,6-naphthyridin-2-onenon-polymer343.72Chemie (A1E5A)
3D, E, G, H, I...
(A, B)
SULFATE IONnon-polymer96.18Chemie (SO4)
4M, N
(A, B)
waterwater18.0416Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63145.9
Non-Polymers*Number of molecules10
Total formula weight1456.0
All*Total formula weight64601.9
*Water molecules are not included.

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PDB entries from 2026-04-01

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