22HA
The crystal structure of BRD4-BD1 in complex with inhibitor C2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 125 | 14883.2 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | B, C (A) | 3-chloranyl-~{N}-(3,4-dimethoxyphenyl)-4-[[(1~{R},2~{S})-2-methyl-3-oxidanylidene-cyclopentyl]amino]benzamide | non-polymer | 402.9 | 2 | Chemie (A1FFR) | |||
| 3 | D (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 44 - 167 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14883.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 805.7 | |
| All* | Total formula weight | 15688.9 |
