21NX
Cryo-EM structure of mouse IgG2b-Fc in complex with FcgammaRIV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Low affinity immunoglobulin gamma Fc region receptor III-A | polymer | 225 | 25763.0 | 1 | UniProt (A0A0B4J1G0) | Mus musculus (house mouse) | IgG Fc receptor III-A,CD16-2,FcgammaRIV |
| 2 | B, C (B, C) | Isoform 2 of Immunoglobulin heavy constant gamma 2B | polymer | 263 | 29472.7 | 2 | UniProt (P01867) | Mus musculus (house mouse) | Ig gamma-2B chain C region |
| 3 | D, E (D, E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 2 | In PDB GlyTouCan (G32152BH) | |||
| 4 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A: 1 - 203 (UniProt: A0A0B4J1G0)
B, C: 209 - 447 (UniProt: P01867)
| PDB | External Database | Details |
|---|---|---|
| Gly 204 | - | expression tag |
| Gly 205 | - | expression tag |
| Ser 206 | - | expression tag |
| His 207 | - | expression tag |
| His 208 | - | expression tag |
| His 209 | - | expression tag |
| His 210 | - | expression tag |
| His 211 | - | expression tag |
| His 212 | - | expression tag |
| His 213 | - | expression tag |
| His 214 | - | expression tag |
| Ser 215 | - | expression tag |
| Arg 216 | - | expression tag |
| Val 217 | - | expression tag |
| Asp 218 | - | expression tag |
| Tyr 219 | - | expression tag |
| Lys 220 | - | expression tag |
| Asp 221 | - | expression tag |
| Asp 222 | - | expression tag |
| Asp 223 | - | expression tag |
| Asp 224 | - | expression tag |
| Lys 225 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 185 | - | initiating methionine |
| Tyr 186 | - | expression tag |
| Arg 187 | - | expression tag |
| Met 188 | - | expression tag |
| Gln 189 | - | expression tag |
| Leu 190 | - | expression tag |
| Leu 191 | - | expression tag |
| Ser 192 | - | expression tag |
| Cys 193 | - | expression tag |
| Ile 194 | - | expression tag |
| Ala 195 | - | expression tag |
| Leu 196 | - | expression tag |
| Ser 197 | - | expression tag |
| Leu 198 | - | expression tag |
| Ala 199 | - | expression tag |
| Leu 200 | - | expression tag |
| Val 201 | - | expression tag |
| Thr 202 | - | expression tag |
| Asn 203 | - | expression tag |
| Ser 204 | - | expression tag |
| Ala 205 | - | expression tag |
| Arg 206 | - | expression tag |
| Ile 207 | - | expression tag |
| His 208 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 84708.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1465.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 86395.0 |
