20YC
Cryo-EM structure of GPR174-Gi complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40458.1 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Galphai,Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (R) | Probable G-protein coupled receptor 174 | polymer | 333 | 38539.5 | 1 | UniProt (Q9BXC1) Pfam (PF00001) | Homo sapiens (human) | |
| 3 | C (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 338 | 37198.7 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 4 | D (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | Ggamma2,G gamma-I |
Sequence modifications
A: 1 - 354 (UniProt: P63096)
| PDB | External Database | Details |
|---|---|---|
| Asn 47 | Ser 47 | conflict |
| Ser 326 | Ala 326 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 124057.4 | |
| All* | Total formula weight | 124057.4 |
