1ZZU
Rat nNOS D597N/M336V double mutant with L-N(omega)-Nitroarginine-2,4-L-Diaminobutyric Amide Bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric-oxide synthase, brain | polymer | 420 | 48579.2 | 2 | UniProt (P29476) Pfam (PF02898) | Rattus norvegicus (Norway rat) | NOS, type I, Neuronal NOS, N-NOS, nNOS, Constitutive NOS, NC-NOS, BNOS |
| 2 | C, J (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | E, K (A, B) | D-MANNITOL | non-polymer | 182.2 | 2 | Chemie (MTL) | |||
| 5 | F, L (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 6 | G, M (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 7 | H, N (A, B) | L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE | non-polymer | 318.3 | 2 | Chemie (DP1) | |||
| 8 | I, O (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | P, Q (A, B) | water | water | 18.0 | 683 | Chemie (HOH) |
Sequence modifications
A, B: 299 - 718 (UniProt: P29476)
| PDB | External Database | Details |
|---|---|---|
| Val 336 | Met 336 | engineered mutation |
| Asn 597 | Asp 597 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97158.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 3084.2 | |
| All* | Total formula weight | 100242.6 |
