1ZVR
Crystal Structure of MTMR2 in complex with phosphatidylinositol 3,5-bisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myotubularin-related protein 2 | polymer | 528 | 61104.4 | 1 | UniProt (Q13614) Pfam (PF02893) Pfam (PF06602) | Homo sapiens (human) | |
| 2 | B, C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (A) | (1S)-2-(1-HYDROXYBUTOXY)-1-{[(HYDROXY{[(2R,3S,5R,6S)-2,4,6-TRIHYDROXY-3,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTYRATE | non-polymer | 636.4 | 1 | Chemie (3PI) | |||
| 4 | F (A) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A: 73 - 586 (UniProt: Q13614)
| PDB | External Database | Details |
|---|---|---|
| Met 70 | - | cloning artifact |
| Ala 71 | - | cloning artifact |
| Ser 72 | - | cloning artifact |
| Ser 417 | Cys 417 | engineered mutation |
| Ala 587 | - | cloning artifact |
| Ala 588 | - | cloning artifact |
| Ala 589 | - | cloning artifact |
| Leu 590 | - | cloning artifact |
| Glu 591 | - | cloning artifact |
| His 592 | - | expression tag |
| His 593 | - | expression tag |
| His 594 | - | expression tag |
| His 595 | - | expression tag |
| His 596 | - | expression tag |
| His 597 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61104.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 822.6 | |
| All* | Total formula weight | 61927.0 |
