1ZUM

Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, Apo Form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Aldehyde dehydrogenase	polymer	500	54499.7	12	UniProt (P05091) Pfam (PF00171) In PDB	Homo sapiens (human)	ALDH class 2, ALDHI, ALDH-E2, ALDH2*2
2	E, F, G, A, H...	SODIUM ION	non-polymer		23.0	12	Chemie (NA)
3	E, F, G, A, H...	GUANIDINE	non-polymer		59.1	8	Chemie (GAI)
4	D, L, E, F, G...	1,2-ETHANEDIOL	non-polymer		62.1	21	Chemie (EDO)
5		water	water		18.0	2649	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 500 (UniProt: P05091)

PDB	External Database	Details
Lys 487	Glu 504	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	653996.3
Non-Polymers*	Number of molecules	41
	Total formula weight	2051.9
All*	Total formula weight	656048.2

*Water molecules are not included.