1ZLT
Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase Chk1 | polymer | 295 | 33871.9 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | Homo sapiens (human) | |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A | (4Z)-4-(2-AMINO-5-OXO-3,5-DIHYDRO-4H-IMIDAZOL-4-YLIDENE)-2,3-DICHLORO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8(1H)-ONE | non-polymer | 314.1 | 1 | Chemie (HYM) | |||
| 4 | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: O14757)
| PDB | External Database | Details |
|---|---|---|
| His 290 | - | expression tag |
| His 291 | - | expression tag |
| His 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33871.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 410.2 | |
| All* | Total formula weight | 34282.0 |
