1ZH6

Crystal Structure of p-acetylphenylalanine-tRNA synthetase in complex with p-acetylphenylalanine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tyrosyl-tRNA synthetase	polymer	314	36099.9	1	UniProt (Q57834) Pfam (PF00579)	Methanocaldococcus jannaschii	Tyrosine--tRNA ligase, TyrRS
2	B (A)	4-ACETYL-L-PHENYLALANINE	non-polymer		207.2	1	Chemie (4AF)
3	C, D (A)	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
4	E (A)	water	water		18.0	80	Chemie (HOH)

Sequence modifications

A: 1 - 306 (UniProt: Q57834)

PDB	External Database	Details
Leu 32	Tyr 32	engineered mutation
Gly 158	Asp 158	engineered mutation
Cys 159	Ile 159	engineered mutation
Arg 162	Leu 162	engineered mutation
Leu 307	-	cloning artifact
Glu 308	-	cloning artifact
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36099.9
Non-Polymers*	Number of molecules	3
	Total formula weight	363.5
All*	Total formula weight	36463.4

*Water molecules are not included.