1ZET
X-ray data do not support hoogsteen base-pairing during replication by human polymerase iota
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | 5'-D(P*AP*GP*GP*GP*(BRU)P*CP*CP*(BRU)P*(BRU)P*CP*CP*CP*CP*C)-3' | polymer | 14 | 4387.3 | 1 | |||
| 2 | B (P) | 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*(DOC))-3' | polymer | 13 | 4050.6 | 1 | |||
| 3 | C (A) | Polymerase (DNA directed) iota | polymer | 388 | 43878.9 | 1 | GenBank (21619716) Pfam (PF00817) Pfam (PF21999) Pfam (PF11799) UniProt (by SIFTS) (Q9UNA4) | Homo sapiens (human) | |
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 6 | F, G, H (T, P, A) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52316.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 506.5 | |
| All* | Total formula weight | 52823.3 |
