1ZEO
Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator activated receptor gamma | polymer | 277 | 31593.6 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma |
| 2 | A | (2S)-(4-ISOPROPYLPHENYL)[(2-METHYL-3-OXO-5,7-DIPROPYL-2,3-DIHYDRO-1,2-BENZISOXAZOL-6-YL)OXY]ACETATE | non-polymer | 424.5 | 1 | Chemie (C01) | |||
| 3 | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A, B: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 201 | - | SEE REMARK 999 |
| Ser 202 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63187.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 424.5 | |
| All* | Total formula weight | 63611.8 |
