1ZCZ

Crystal structure of Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase (TM1249) from THERMOTOGA MARITIMA at 1.88 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bifunctional purine biosynthesis protein purH	polymer	464	51392.9	2	UniProt (Q9X0X6) Pfam (PF02142) Pfam (PF01808)	Thermotoga maritima	Phosphoribosylaminoimidazolecarboxamide formyltransferase, IMP cyclohydrolase
2	C, E (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
3	D, F (A, B)	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
4	G, H (A, B)	water	water		18.0	636	Chemie (HOH)

Sequence modifications

A, B: 1 - 452 (UniProt: Q9X0X6)

PDB	External Database	Details
Met -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	102785.7
Non-Polymers*	Number of molecules	4
	Total formula weight	466.6
All*	Total formula weight	103252.4

*Water molecules are not included.