1ZCZ
Crystal structure of Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase (TM1249) from THERMOTOGA MARITIMA at 1.88 A resolution
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0003937 | molecular_function | IMP cyclohydrolase activity |
A | 0004643 | molecular_function | phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006164 | biological_process | purine nucleotide biosynthetic process |
A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016787 | molecular_function | hydrolase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0003937 | molecular_function | IMP cyclohydrolase activity |
B | 0004643 | molecular_function | phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006164 | biological_process | purine nucleotide biosynthetic process |
B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K A 453 |
Chain | Residue |
A | VAL350 |
A | GLU351 |
A | ALA353 |
A | ASP399 |
A | VAL449 |
A | ARG451 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K B 453 |
Chain | Residue |
B | ASP399 |
B | VAL449 |
B | ARG451 |
B | VAL350 |
B | GLU351 |
B | ALA353 |
site_id | AC3 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE PG4 A 454 |
Chain | Residue |
A | GLY157 |
A | LEU160 |
A | ALA161 |
A | PHE162 |
A | TRP306 |
A | HOH550 |
A | HOH576 |
A | HOH648 |
B | PHE180 |
B | TYR182 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PG4 B 454 |
Chain | Residue |
A | PHE180 |
A | TYR182 |
B | LEU160 |
B | ALA161 |
B | PHE162 |
B | TRP306 |
B | HOH514 |
B | HOH594 |