1ZCZ
Crystal structure of Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase (TM1249) from THERMOTOGA MARITIMA at 1.88 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003937 | molecular_function | IMP cyclohydrolase activity |
| A | 0004643 | molecular_function | phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003937 | molecular_function | IMP cyclohydrolase activity |
| B | 0004643 | molecular_function | phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 453 |
| Chain | Residue |
| A | VAL350 |
| A | GLU351 |
| A | ALA353 |
| A | ASP399 |
| A | VAL449 |
| A | ARG451 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 453 |
| Chain | Residue |
| B | ASP399 |
| B | VAL449 |
| B | ARG451 |
| B | VAL350 |
| B | GLU351 |
| B | ALA353 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PG4 A 454 |
| Chain | Residue |
| A | GLY157 |
| A | LEU160 |
| A | ALA161 |
| A | PHE162 |
| A | TRP306 |
| A | HOH550 |
| A | HOH576 |
| A | HOH648 |
| B | PHE180 |
| B | TYR182 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 B 454 |
| Chain | Residue |
| A | PHE180 |
| A | TYR182 |
| B | LEU160 |
| B | ALA161 |
| B | PHE162 |
| B | TRP306 |
| B | HOH514 |
| B | HOH594 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 228 |
| Details | Domain: {"description":"MGS-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU01202","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
