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1Z95

Crystal Structure of the Androgen Receptor Ligand-binding Domain W741L Mutant Complex with R-bicalutamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Androgen Receptorpolymer24628646.71UniProt (P10275)
Pfam (PF00104)
Homo sapiens (human)Dihydrotestosterone receptor
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C
(A)
R-BICALUTAMIDEnon-polymer430.41Chemie (198)
4D
(A)
waterwater18.0134Chemie (HOH)
Sequence modifications
A: 672 - 917 (UniProt: P10275)
PDBExternal DatabaseDetails
Leu 741Trp 740engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28646.7
Non-Polymers*Number of molecules2
Total formula weight526.4
All*Total formula weight29173.1
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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