1Z6Z
Crystal Structure of Human Sepiapterin Reductase in complex with NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Sepiapterin reductase | polymer | 282 | 30550.1 | 6 | UniProt (P35270) Pfam (PF00106) | Homo sapiens (human) | SPR |
| 2 | G (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | H, I, K, M, N... (A, B, C, D, E...) | CHLORIDE ION | non-polymer | 35.5 | 11 | Chemie (CL) | |||
| 4 | J, L, P, S, V... (A, B, C, D, E...) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 6 | Chemie (NAP) | |||
| 5 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 258 (UniProt: P35270)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | cloning artifact |
| Gly -20 | - | cloning artifact |
| Ser -19 | - | cloning artifact |
| Ser -18 | - | cloning artifact |
| His -17 | - | cloning artifact |
| His -16 | - | cloning artifact |
| His -15 | - | cloning artifact |
| His -14 | - | cloning artifact |
| His -13 | - | cloning artifact |
| His -12 | - | cloning artifact |
| Ser -11 | - | cloning artifact |
| Ser -10 | - | cloning artifact |
| Gly -9 | - | cloning artifact |
| Arg -8 | - | cloning artifact |
| Glu -7 | - | cloning artifact |
| Asn -6 | - | cloning artifact |
| Leu -5 | - | cloning artifact |
| Tyr -4 | - | cloning artifact |
| Phe -3 | - | cloning artifact |
| Gln -2 | - | cloning artifact |
| Gly -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
| Met 1 | - | cloning artifact |
| Gly 259 | - | cloning artifact |
| Ser 260 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 183300.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4946.5 | |
| All* | Total formula weight | 188247.0 |
