1Z6E
Factor XA in complex with the inhibitor 1-(3'-amino-1,2-benzisoxazol-5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (razaxaban; DPC906; BMS-561389)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor X | polymer | 234 | 26447.1 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 2 | B (L) | Coagulation factor X | polymer | 52 | 5589.2 | 1 | UniProt (P00742) Pfam (PF14670) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 3 | C (A) | 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL) -1H-PYRAZOLE-5-CARBOXAMIDE | non-polymer | 528.5 | 1 | Chemie (IK8) | |||
| 4 | D, E (A, L) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32036.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 528.5 | |
| All* | Total formula weight | 32564.8 |
