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1Z69

Crystal structure of methylenetetrahydromethanopterin reductase (Mer) in complex with coenzyme F420

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductasepolymer32734501.94GenBank (48840204)
Pfam (PF00296)
UniProt (by SIFTS) (Q46FV4)
Methanosarcina barkeriCOG2141; Methylene-H(4)MPT reductase
2E, G, H, J
(A, B, C, D)
COENZYME F420non-polymer773.64Chemie (F42)
3F, I
(B, D)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4K
(D)
2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOLnon-polymer252.31Chemie (1PG)
5L, M, N, O
(A, B, C, D)
waterwater18.0239Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight138007.8
Non-Polymers*Number of molecules7
Total formula weight3417.6
All*Total formula weight141425.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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