1Z4S

Crystal Structure of Gly19 and Glu60 deletion mutant of Human Acidic Fibroblast Growth Factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Heparin-binding growth factor 1	polymer	144	16500.6	4	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF- beta
2	E, F (B, C)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	G, H, I, J (A, B, C, D)	water	water		18.0	90	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
-	Gly 34	deletion
-	Glu 75	deletion

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66002.3
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	66194.5

*Water molecules are not included.