1Z4L
Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with thymidine 5'-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'(3')-deoxyribonucleotidase | polymer | 197 | 22840.1 | 1 | UniProt (Q9NPB1) Pfam (PF06941) | Homo sapiens (human) | Mitochondrial deoxyribonucleotidase, 5',3'-nucleotidase, mitochondrial, Deoxy-5'-nucleotidase 2, dNT-2 |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (444919) PubChem (9700) PubChem (5274091) PubChem (5748250) PubChem (10147784) PubChem (129069890) PubChem (133126478) PubChem (164603144) | |||
| 4 | E (A) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A: 32 - 228 (UniProt: Q9NPB1)
| PDB | External Database | Details |
|---|---|---|
| Asn 41 | Asp 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22840.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 370.8 | |
| All* | Total formula weight | 23211.0 |
