1Z4J
Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with uridine 2'-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'(3')-deoxyribonucleotidase | polymer | 197 | 22840.1 | 1 | UniProt (Q9NPB1) Pfam (PF06941) | Homo sapiens (human) | Mitochondrial deoxyribonucleotidase, 5',3'-nucleotidase, mitochondrial, Deoxy-5'-nucleotidase 2, dNT-2 |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER | non-polymer | 324.2 | 1 | Chemie (U2P) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 32 - 228 (UniProt: Q9NPB1)
| PDB | External Database | Details |
|---|---|---|
| Asn 41 | Asp 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22840.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 464.9 | |
| All* | Total formula weight | 23305.0 |
