1Z1A

S. cerevisiae Sir1 ORC-interaction domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Regulatory protein SIR1	polymer	142	16846.1	2	UniProt (P21691) Pfam (PF11603)	Saccharomyces cerevisiae (baker's yeast)	Silent information regulator 1
2	C, D (A, B)	water	water		18.0	43	Chemie (HOH)

Sequence modifications

A, B: 473 - 611 (UniProt: P21691)

PDB	External Database	Details
Gly 470	-	cloning artifact
Ser 471	-	cloning artifact
His 472	-	cloning artifact
Mse 528	Met 528	modified residue
Mse 532	Met 532	modified residue
Mse 589	Met 589	modified residue
Cys 558	Ala 593	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33692.2
All*	Total formula weight	33692.2

*Water molecules are not included.