1Z0K
Structure of GTP-Bound Rab4Q67L GTPase in complex with the central Rab binding domain of Rabenosyn-5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | GTP-binding protein | polymer | 172 | 19392.0 | 2 | UniProt (P20338) Pfam (PF00071) | Homo sapiens (human) | |
| 2 | B, D (B, D) | FYVE-finger-containing Rab5 effector protein rabenosyn-5 | polymer | 69 | 7716.4 | 2 | UniProt (Q59EY8) Pfam (PF11464) UniProt (by SIFTS) (Q9H1K0) | Homo sapiens (human) | |
| 3 | E, G (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, H (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | I (D) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 6 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 457 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 172 (UniProt: P20338)
B, D: 440 - 503 (UniProt: Q59EY8)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Leu 67 | Gln 67 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 435 | - | cloning artifact |
| Pro 436 | - | cloning artifact |
| Leu 437 | - | cloning artifact |
| Gly 438 | - | cloning artifact |
| Ser 439 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54216.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1290.2 | |
| All* | Total formula weight | 55507.0 |
