1YXV
Crystal Structure of Kinase Pim1 in complex with 3,4-Dihydroxy-1-methylquinolin-2(1H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene serine/threonine-protein kinase Pim-1 | polymer | 293 | 33832.3 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 3 | C (A) | 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE | non-polymer | 191.2 | 1 | Chemie (LI6) PubChem (54695768) | |||
| 4 | D (A) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 29 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Val 314 | - | expression tag |
| Asp 315 | - | expression tag |
| His 316 | - | expression tag |
| His 317 | - | expression tag |
| His 318 | - | expression tag |
| His 319 | - | expression tag |
| His 320 | - | expression tag |
| His 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33832.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 260.3 | |
| All* | Total formula weight | 34092.6 |
