1YXU
Crystal Structure of Kinase Pim1 in Complex with AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Proto-oncogene serine/threonine-protein kinase Pim-1 | polymer | 293 | 33832.3 | 4 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | E, G, I, K (A, B, C, D) | IMIDAZOLE | non-polymer | 69.1 | 4 | Chemie (IMD) | |||
| 3 | F, H, J, L (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 29 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Val 314 | - | expression tag |
| Asp 315 | - | expression tag |
| His 316 | - | expression tag |
| His 317 | - | expression tag |
| His 318 | - | expression tag |
| His 319 | - | expression tag |
| His 320 | - | expression tag |
| His 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 135329.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1665.2 | |
| All* | Total formula weight | 136994.5 |
