1YXU

Crystal Structure of Kinase Pim1 in Complex with AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Proto-oncogene serine/threonine-protein kinase Pim-1	polymer	293	33832.3	4	UniProt (P11309) Pfam (PF00069)	Homo sapiens (human)
2	E, G, I, K (A, B, C, D)	IMIDAZOLE	non-polymer		69.1	4	Chemie (IMD)
3	F, H, J, L (A, B, C, D)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	4	Chemie (AMP)
4	M, N, O, P (A, B, C, D)	water	water		18.0	384	Chemie (HOH)

Sequence modifications

A, B, C, D: 29 - 313 (UniProt: P11309)

PDB	External Database	Details
Val 314	-	expression tag
Asp 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135329.3
Non-Polymers*	Number of molecules	8
	Total formula weight	1665.2
All*	Total formula weight	136994.5

*Water molecules are not included.