1YT1

Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Endoplasmin	polymer	236	26514.0	2	UniProt (P41148) Pfam (PF13589) In PDB	Canis lupus familiaris (dog)	94 kDa glucose-regulated protein, GRP94
2	A, B	TETRAETHYLENE GLYCOL	non-polymer		194.2	11	Chemie (PG4)
3	B	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
4		water	water		18.0	445	Chemie (HOH)

Sequence modifications

A, B: 69 - 286 (UniProt: P41148)

PDB	External Database	Details
Gly 65	-	cloning artifact
Ser 66	-	cloning artifact
His 67	-	cloning artifact
Met 68	-	cloning artifact

A, B: 328 - 337 (UniProt: P41148)

PDB	External Database	Details
Gly 324	-	SEE REMARK 999
Gly 325	-	SEE REMARK 999
Gly 326	-	SEE REMARK 999
Gly 327	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53028.0
Non-Polymers*	Number of molecules	12
	Total formula weight	2374.8
All*	Total formula weight	55402.8

*Water molecules are not included.