1YSL

Crystal structure of HMG-CoA synthase from Enterococcus faecalis with AcetoAcetyl-CoA ligand.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HMG-CoA synthase	polymer	402	44307.9	1	GenBank (9937383) Pfam (PF01154) Pfam (PF08540) UniProt (by SIFTS) (Q9FD71)	Enterococcus faecalis
2	B (B)	HMG-CoA synthase	polymer	402	44275.9	1	GenBank (9937383) Pfam (PF01154) Pfam (PF08540) UniProt (by SIFTS) (Q9FD71)	Enterococcus faecalis
3	C, E (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	D, H (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	F (B)	COENZYME A	non-polymer		767.5	1	Chemie (COA)
6	G (B)	ACETOACETIC ACID	non-polymer		102.1	1	Chemie (AAE)
7	I, J (A, B)	water	water		18.0	522	Chemie (HOH)

Sequence modifications

A: 1 - 383 (GenBank: 9937383)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

B: 1 - 383 (GenBank: 9937383)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Csd 111	Cys 111	microheterogeneity

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88583.7
Non-Polymers*	Number of molecules	6
	Total formula weight	1245.9
All*	Total formula weight	89829.6

*Water molecules are not included.