1YQR
Catalytically inactive human 8-oxoguanine glycosylase crosslinked to oxoG containing DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3' | polymer | 14 | 4345.8 | 1 | |||
| 2 | B (C) | 5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3' | polymer | 14 | 4232.7 | 1 | |||
| 3 | C (A) | N-glycosylase/DNA lyase | polymer | 319 | 35970.7 | 1 | UniProt (O15527) Pfam (PF07934) Pfam (PF00730) | Homo sapiens (human) | |
| 4 | D, E (C, A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F, G, H (B, C, A) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A: 12 - 327 (UniProt: O15527)
| PDB | External Database | Details |
|---|---|---|
| Ser 9 | - | cloning artifact |
| Glu 10 | - | cloning artifact |
| Phe 11 | - | cloning artifact |
| Cys 149 | Asn 149 | engineered mutation |
| Gln 249 | Lys 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44549.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 44629.4 |
