1YOV
Insights into the Ubiquitin Transfer Cascade from the refined structure of the activating enzyme for NEDD8
Replaces: 1NGVEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Amyloid protein-binding protein 1 | polymer | 537 | 60688.6 | 2 | UniProt (Q13564) Pfam (PF00899) | Homo sapiens (human) | Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Protooncogene protein 1, HPP1 |
| 2 | B, D (B, D) | Ubiquitin-activating enzyme E1C | polymer | 444 | 49534.4 | 2 | UniProt (Q8TBC4) Pfam (PF00899) Pfam (PF08825) | Homo sapiens (human) | Nedd8-activating enzyme E1C, Ubiquitin-activating enzyme 3 homolog |
| 3 | E, F (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 534 (UniProt: Q13564)
B, D: 1 - 442 (UniProt: Q8TBC4)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | cloning artifact |
| Lys -1 | - | cloning artifact |
| Leu 0 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 220446.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 220577.0 |
