1YNK
Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeteners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | immunoglobulin kappa light chain | polymer | 219 | 24123.8 | 1 | Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (A2P1G9) | Mus musculus (house mouse) | NC6.8 Fab fragment L-chain, monoclonal antibody Fab fragment |
| 2 | B (H) | Ig gamma heavy chain | polymer | 219 | 23355.0 | 1 | UniProt (Q6PJB2) Pfam (PF07686) Pfam (PF07654) | Mus musculus (house mouse) | NC6.8 Fab fragment H-chain |
| 3 | C (H) | 2-[((R)-{[4-(AMINOMETHYL)PHENYL]AMINO}{[(1R)-1-PHENYLETHYL]AMINO}METHYL)AMINO]ETHANE-1,1-DIOL | non-polymer | 330.4 | 1 | Chemie (SC5) | |||
| 4 | D, E (L, H) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47478.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 330.4 | |
| All* | Total formula weight | 47809.3 |
