1YE4
Crystal structure of the Lys-274 to Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NAD(P)H-dependent D-xylose reductase | polymer | 322 | 36090.2 | 4 | UniProt (O74237) Pfam (PF00248) | Candida tenuis | XR |
| 2 | E, G, H, J, L... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | F, I, K, N (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 681 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 322 (UniProt: O74237)
| PDB | External Database | Details |
|---|---|---|
| Arg 274 | Lys 274 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 144360.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3230.1 | |
| All* | Total formula weight | 147590.9 |
