1YCP
THE CRYSTAL STRUCTURE OF FIBRINOGEN-AA PEPTIDE 1-23 (F8Y) BOUND TO BOVINE THROMBIN EXPLAINS WHY THE MUTATION OF PHE-8 TO TYROSINE STRONGLY INHIBITS NORMAL CLEAVAGE AT ARGININE-16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (L, J) | EPSILON THROMBIN | polymer | 49 | 5735.2 | 2 | UniProt (P00735) Pfam (PF09396) | Bos taurus (cattle) | |
| 2 | B (H) | ALPHA THROMBIN | polymer | 259 | 29772.4 | 1 | UniProt (P00735) Pfam (PF00089) | Bos taurus (cattle) | |
| 3 | C, G (F, N) | FIBRINOPEPTIDE A-ALPHA | polymer | 23 | 2349.5 | 2 | UniProt (P02671) | ||
| 4 | E (K) | EPSILON THROMBIN | polymer | 150 | 17525.3 | 1 | UniProt (P00735) Pfam (PF00089) | Bos taurus (cattle) | |
| 5 | F (M) | EPSILON THROMBIN | polymer | 109 | 12265.1 | 1 | UniProt (P00735) Pfam (PF00089) | Bos taurus (cattle) | |
| 6 | H, I, J, K, L... (L, H, F, J, K...) | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence modifications
F, N: 301 - 323 (UniProt: P02671)
| PDB | External Database | Details |
|---|---|---|
| Tyr 308 | Phe | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 75732.3 | |
| All* | Total formula weight | 75732.3 |
