Functional Information from GO Data
| Chain | GOid | namespace | contents |
| H | 0004252 | molecular_function | serine-type endopeptidase activity |
| H | 0005509 | molecular_function | calcium ion binding |
| H | 0006508 | biological_process | proteolysis |
| H | 0007596 | biological_process | blood coagulation |
| J | 0004252 | molecular_function | serine-type endopeptidase activity |
| J | 0005576 | cellular_component | extracellular region |
| J | 0006508 | biological_process | proteolysis |
| J | 0007596 | biological_process | blood coagulation |
| K | 0004252 | molecular_function | serine-type endopeptidase activity |
| K | 0005509 | molecular_function | calcium ion binding |
| K | 0006508 | biological_process | proteolysis |
| K | 0007596 | biological_process | blood coagulation |
| L | 0004252 | molecular_function | serine-type endopeptidase activity |
| L | 0005576 | cellular_component | extracellular region |
| L | 0006508 | biological_process | proteolysis |
| L | 0007596 | biological_process | blood coagulation |
| M | 0004252 | molecular_function | serine-type endopeptidase activity |
| M | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR CHAIN F OF FIBRINOPEPTIDE A-ALPHA |
| Chain | Residue |
| F | HOH450 |
| H | GLU97 |
| H | LEU99 |
| H | ILE174 |
| H | ASP189 |
| H | ALA190 |
| H | CYS191 |
| H | GLU192 |
| H | GLY193 |
| H | SER195 |
| H | SER214 |
| F | HOH481 |
| H | TRP215 |
| H | GLY216 |
| H | GLY219 |
| H | HOH411 |
| F | HOH482 |
| F | HOH668 |
| H | LEU41 |
| H | HIS57 |
| H | TYR60 |
| H | TRP96 |
| H | LYS97 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR CHAIN N OF FIBRINOPEPTIDE A-ALPHA |
| Chain | Residue |
| H | TRP60 |
| H | HOH504 |
| K | HIS57 |
| K | LYS97 |
| K | GLU97 |
| K | HOH442 |
| K | HOH495 |
| M | ILE174 |
| M | ASP189 |
| M | GLU192 |
| M | GLY193 |
| M | SER195 |
| M | SER214 |
| M | TRP215 |
| M | GLY216 |
| M | GLY219 |
Functional Information from PROSITE/UniProt
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAceGDSGGPFV |
| Chain | Residue | Details |
| M | ASP189-VAL200 | |
| H | ASP189-VAL200 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| K | LEU53-CYS58 | |
| H | LEU53-CYS58 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by thrombin; to release fibrinopeptide A |
| Chain | Residue | Details |
| F | ARG316 | |
| N | ARG316 | |
| H | SER195 | |
| Chain | Residue | Details |
| F | SER303 | |
| N | SER303 | |
