1YC5
Sir2-p53 peptide-nicotinamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-dependent deacetylase | polymer | 246 | 27569.8 | 1 | UniProt (Q9WYW0) Pfam (PF02146) | Thermotoga maritima | Regulatory protein SIR2 homolog |
| 2 | B (B) | Cellular tumor antigen p53 peptide | polymer | 18 | 2139.5 | 1 | UniProt (Q9NP68) UniProt (by SIFTS) (P04637) | Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13 | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | NICOTINAMIDE | non-polymer | 122.1 | 1 | Chemie (NCA) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
B: 372 - 389 (UniProt: Q9NP68)
| PDB | External Database | Details |
|---|---|---|
| Aly 382 | Lys 382 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29709.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 187.5 | |
| All* | Total formula weight | 29896.8 |
