1YA5
Crystal structure of the titin domains z1z2 in complex with telethonin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | N2B-TITIN ISOFORM | polymer | 201 | 21583.0 | 2 | UniProt (Q6PJP0) Pfam (PF07679) UniProt (by SIFTS) (Q8WZ42) In PDB | Homo sapiens (human) | TTN protein; titin isoform novex-2; titin isoform novex-1 |
| 2 | T | TELETHONIN | polymer | 90 | 10619.7 | 1 | UniProt (O15273) Pfam (PF09470) In PDB | Homo sapiens (human) | Titin cap protein |
| 3 | A, B, T | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 196 (UniProt: Q6PJP0)
T: 1 - 90 (UniProt: O15273)
| PDB | External Database | Details |
|---|---|---|
| Thr 197 | - | cloning artifact |
| Arg 198 | - | cloning artifact |
| Glu 199 | - | cloning artifact |
| Glu 200 | - | cloning artifact |
| Phe 201 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Ser 8 | Cys 8 | engineered mutation |
| Ser 15 | Cys 15 | engineered mutation |
| Ser 38 | Cys 38 | engineered mutation |
| Ser 57 | Cys 57 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 53785.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 480.3 | |
| All* | Total formula weight | 54266.0 |
