1Y91

Crystal structure of human CDK2 complexed with a pyrazolo[1,5-a]pyrimidine inhibitor

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
ACell division protein kinase 2polymer29833976.51
UniProt (P24941)
Pfam (PF00069)
Homo sapiens (human)@PDBjp33 protein kinase
4-[5-(TRANS-4-AMINOCYCLOHEXYLAMINO)-3-ISOPROPYLPYRAZOLO[1,5-A]PYRIMIDIN-7-YLAMINO]-N,N-DIMETHYLBENZENESULFONAMIDEnon-polymer471.61
waterwater18.0190

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains1
Total molecular weight33976.5
Non-Polymers*Number of molecules1
Total molecular weight471.6
All*Total molecular weight34448.1
*Water molecules are not included.